Interrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory response

dc.contributor.authorMysula, Ihorpl
dc.contributor.authorBondarchuk, Valentynapl
dc.contributor.authorWójcik, Gustawpl
dc.contributor.authorZukow, Walerypl
dc.contributor.authorSydliaruk, Nataliyapl
dc.contributor.authorMysula, Yuriypl
dc.contributor.authorMysula, Mariannapl
dc.date.accessioned2019-10-04T10:02:19Z
dc.date.available2019-10-04T10:02:19Z
dc.date.issued2019-10-01pl
dc.description.abstractregarding the connection of morphometric and biochemical changes in oral mucous membrane of animals with gastroduodenitis depending on the type of inflammatory response. For this reason, it remains important to study the relationship between changes in the morphometric parameters of the oral mucosa, lipid peroxidation indices and the antioxidant system under the influence of various types of inflammatory reaction in the conditions of experimental gastroduodenitis. Material and methods. Experiments were carried out on 42 white male rats weighing 180-200 g housed under normal conditions on a standard vivarium diet; acute gastroduodenitis was simulated for 7 days by inserting by the probe into the stomach 0.25 ml of 10% solution C2H5OH and after 5 minutes 0.5 ml of 1.25% solution of HCl. Three different types of inflammatory response were also modeled. Results. The most significant changes in oral mucosa on the basis of morphometric and biochemical parameters were found in animals with hyperergic type of inflammatory reaction. Rats with hypoergic type of inflammatory reaction had a lower depth of morphometric and biochemical changes. Morphometric changes were most significant on the tenth day of the experiment, regardless of the type of inflammatory reaction. Conclusions. The obtained results confirm that changes in morphometric and biochemical parameters depend on the type of inflammatory reaction.en
dc.identifier.citationJournal of Education, Health and Sport, No. 10, Vol. 9, pp. 22-35pl
dc.identifier.issn2391-8306pl
dc.identifier.otherdoi:10.5281/zenodo.3471770pl
dc.identifier.urihttp://repozytorium.umk.pl/handle/item/6107
dc.language.isoengpl
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 Internationalpl
dc.rightsinfo:eu-repo/semantics/openAccesspl
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pl
dc.subjectcheeken
dc.subjectmucous membraneen
dc.subjectmorphometric parametersen
dc.subjectbiochemical changesen
dc.subjecttype of inflammatory responseen
dc.subjectgastroduodenitis.en
dc.titleInterrelation of morphometric and biochemical changes in oral mucous membrane in animals with gastroduodenitis depending on the inflammatory responsepl
dc.typeinfo:eu-repo/semantics/articlepl

Files

Original bundle

Loading...
Thumbnail Image
Name:
7564,Mysula,Bondarchuk,Wojcik_et_al.pdf
Size:
479.9 KB
Format:
Adobe Portable Document Format