Sodium nitrate affects myocardium in pregnant rats and their pups

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dc.contributor.author Sataieva, Tatiana
dc.contributor.author Zadnipryany, Igor
dc.contributor.author Żukow, Walery
dc.date.accessioned 2019-02-01T08:12:46Z
dc.date.available 2019-02-01T08:12:46Z
dc.date.issued 2018-08-01
dc.identifier.citation Ecological Questions, No. 4, Vol. 29, pp. 55-62.
dc.identifier.issn 1644-7298
dc.identifier.other doi:10.12775/EQ.2018.029
dc.identifier.uri http://repozytorium.umk.pl/handle/item/5595
dc.description.abstract The problem of pollution with nitrates and nitrites of the natural environment is very relevant nowadays. The purpose of this research was to study the morphological features of the myocardium in pregnant rats and their newborn pups exposed to chronic hemic hypoxia induced by sodium nitrite. The changes in the contractile apparatus of cardiomyocytes were atrophy and lysis of myofibrils which were most pronounced at the periphery of the cardiomyocytes, near the capillaries. A similar condition of the microcirculatory vessels accompanies absolutely all types of cardiomyopathies, regardless of the genesis of the disease. Cell-stromal relationships on the background of chronic myocardial ischemia cause destructive processes of myocardial remodeling. The final morphological outcome of prolonged hypoxic heart damage can be focal dystrophy of the myocardium, which leads to the development of chronic heart failure and the appearance of life-threatening arrhythmias.
dc.language.iso eng
dc.rights Attribution-NoDerivs 3.0 Poland
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri http://creativecommons.org/licenses/by-nd/3.0/pl/
dc.subject sodium nitrite
dc.subject hypoxia
dc.subject myocardium
dc.subject rats
dc.subject microscopy
dc.title Sodium nitrate affects myocardium in pregnant rats and their pups
dc.type info:eu-repo/semantics/article

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