ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age

Repository of Nicolaus Copernicus University

Show simple item record

dc.contributor.author Marciniak, Anna
dc.contributor.author Kłoska, Sylwester
dc.contributor.author Woźniak, Marcin
dc.contributor.author Perkowski, Radosław
dc.contributor.author Podhorecka, Marta
dc.contributor.author Gębka, Dominika
dc.contributor.author Androsiuk-Perkowska, Joanna
dc.contributor.author Kozłowski, Henryk
dc.contributor.author Kędziora-Kornatowska, Kornelia
dc.contributor.author Żukow, Walery
dc.date.accessioned 2018-08-16T12:30:20Z
dc.date.available 2018-08-16T12:30:20Z
dc.date.issued 2018-07-30
dc.identifier.citation Journal of Education, Health and Sport, No. 9, Vol. 8, pp. 146-154
dc.identifier.issn 2391-8306
dc.identifier.other doi:10.5281/zenodo.1345224
dc.identifier.uri http://repozytorium.umk.pl/handle/item/5374
dc.description.abstract Among older people, a big problem is the decrease in both muscle strength and general physical fitness. This often prevents the proper functioning of a person, which makes him or her dependent on their guardians or family. It is believed that the ACE gene is associated with better results achieved in strength sports. It may also be related to the health condition of older people. For this purpose, a study was conducted on a group of 60 people over 60 years of age. The study was conducted with the consent of the bioethical commission and under the supervision of physiotherapists. The relationship between overall fitness and muscle strength of older people with ACE genotypic variants was checked. For this purpose, a questionnaire on physical activity of IPAQ was used. On its basis, the values ​​of MET and BMI coefficients were determined. Fitness tests were also carried out, i.e. SPPB, DGI and Up & Go. The ACE gene was tested by PCR. The insertion-deletion polymorphism of the Alu sequence in this gene was examined. It was found that: DD gene genotype ACE is associated with higher values ​​of BMI and shorter standing time on the left leg (p<0.05), genotype II is associated with lower overall physical activity determined on the basis of MET (p<0.05), genotype ID is associated with better results in the left leg test (p<0.05). Based on obtained results it is impossible to determine if ACE gene has clear impact on muscle strength and health of the older adults.
dc.language.iso eng
dc.rights Attribution-NonCommercial-ShareAlike 4.0 International
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject ACE
dc.subject older adults
dc.subject physical performance tests
dc.subject sport genetics
dc.title ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age
dc.type info:eu-repo/semantics/article

Files in this item

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-ShareAlike 4.0 International Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International

Search repository

Advanced Search


My Account